Cervical cancer is a type of cancer that occurs in the cells of the cervix — the lower part of the uterus that connects to the vagina. Various strains of the human papillomavirus HPV , a sexually transmitted infection, play a role in causing most cervical cancer. When exposed to HPV , the body's immune system typically prevents the virus from doing harm. In a small percentage of people, however, the virus survives for years, contributing to the process that causes some cervical cells to become cancer cells. You can reduce your risk of developing cervical cancer by having screening tests and receiving a vaccine that protects against HPV infection.
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Squamous Cell Carcinoma of Vagina
Pathology Outlines - Vaginal intraepithelial neoplasia (VAIN)
High grade squamous intraepithelial lesion or HSIL is a finding on the cervical tissues following a Pap smear. HSIL is a type of cervical dysplasia found in microscopic analysis of the cervical cells. Cervical dysplasia refers to the occurrence of pre-malignant or precancerous cells in the cervix and opening of the uterus. With this regard, HSIL indicates a moderate dysplasia to severe neoplasia of the cervical cells that may mean carcinoma in situ. HSIL is different from low grade squamous intraepithelial lesion or LSIL in which the former have more defined changes in the shape and size of the cervical cells.
What is Squamous Dysplasia?
In most cases, cervical cancer is a slow-progressing disease that often takes years to develop. Before any cancer develops, the cervix the narrow neck of a woman's uterus undergoes abnormal changes called cervical dysplasia. When caught at an early stage, cervical cancer is easier to treat and the survival rates are highest.
A pre-cancer is a condition where some cells look abnormal. These cell changes are not cancer, but could become cancer over time. Vaginal intraepithelial neoplasia or VAIN means that the changed cells are only found in the innermost surface layer of the vagina. VAIN is more common in women who have had their uterus removed hysterectomy and in those who were treated for cervical cancer or pre-cancer in the past. VAIN3 is the closest to a true cancer.